TargetMol

LY 195448

Product Code:
 
TAR-T27891
Product Group:
 
Inhibitors and Activators
Supplier:
 
TargetMol
Regulatory Status:
 
RUO
Shipping:
 
cool pack
Storage:
 
-20℃
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CodeSizePrice
TAR-T27891-5mg5mg£850.00
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TAR-T27891-50mg50mg£1,661.00
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Quantity:
TAR-T27891-100mg100mg£2,079.00
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This product comes from: United States.
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Further Information

Bioactivity:
LY 195448 is a phenethanolamine shown anti-tumour activity. It blocks cells at metaphase.
CAS:
111112-18-6
Formula:
C20H27ClN2O2
Molecular Weight:
362.9
Purity:
0.98
SMILES:
Cl.CC(C)(CCc1ccc(cc1)C(N)=O)NC[C@H](O)c1ccccc1

References

1. Barlow SB, Cabral F. Alterations in microtubule assembly caused by the microtubule-active drug LY195448. Cell Motil Cytoskeleton. 1991;19(1):9-17. PubMed PMID: 1863984. 2. Engineer MS, Newman RA. High-performance liquid chromatographic measurement of (R)-4-[3-[(2-hydroxy-2-phenethyl)amino]-3-methylbutyl]benzamide monohydrochloride (LY195448) and its p-hydroxy metabolite in human plasma and urine. J Chromatogr. 1990 May 18;527(2):473-80. PubMed PMID: 2387891. 3. Ho BT, Tansey LW, Engineer MS, Newman RA, Siddik ZH, Field WS, Krakoff IH. Beta-adrenoceptor binding studies with LY195448 and metabolites. Res Commun Chem Pathol Pharmacol. 1990 Jan;67(1):143-6. PubMed PMID: 2158135. 4. Ho DH, Covington WP, Lin J, Brown NS, Newman RA. Metabolism and disposition of (R)-4-[3-(2-hydroxy-2-phenyl)ethylamino-3-methylbutyl]benzamide Hcl (LY 195448) in rodents. Res Commun Chem Pathol Pharmacol. 1989 Nov;66(2):255-67. PubMed PMID: 2602657.