TargetMol

LY 293284

Product Code:
 
TAR-T27914
Product Group:
 
Inhibitors and Activators
Supplier:
 
TargetMol
Regulatory Status:
 
RUO
Shipping:
 
cool pack
Storage:
 
-20℃
1 / 1
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CodeSizePrice
TAR-T27914-5mg5mg£1,492.00
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TAR-T27914-50mg50mg£2,946.00
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Quantity:
TAR-T27914-100mg100mg£4,006.00
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This product comes from: United States.
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Further Information

Bioactivity:
LY 293284 is a potent, selective full agonist of 5-HT1A receptor with anxiogenic effects in animal studies.
CAS:
141318-62-9
Formula:
C19H26N2O
Molecular Weight:
298.43
Purity:
0.98
SMILES:
CCCN(CCC)[C@H]1Cc2c[nH]c3ccc(C(C)=O)c(C1)c23

References

1. Marona-Lewicka D, Nichols DE. WAY 100635 produces discriminative stimulus effects in rats mediated by dopamine D(4) receptor activation. Behav Pharmacol. 2009 Feb;20(1):114-8. doi: 10.1097/FBP.0b013e3283242f1a. PubMed PMID: 19179855. 2. Marona-Lewicka D, Nichols DE. Aripiprazole (OPC-14597) fully substitutes for the 5-HT1A receptor agonist LY293284 in the drug discrimination assay in rats. Psychopharmacology (Berl). 2004 Apr;172(4):415-21. Epub 2003 Nov 28. PubMed PMID: 14647959. 3. Lisinicchia JG, Watts VJ. Sensitization of adenylate cyclase by short-term activation of 5-HT1A receptors. Cell Signal. 2003 Dec;15(12):1111-7. PubMed PMID: 14575866. 4. Marona-Lewicka D, Kurrasch-Orbaugh DM, Selken JR, Cumbay MG, Lisnicchia JG, Nichols DE. Re-evaluation of lisuride pharmacology: 5-hydroxytryptamine1A receptor-mediated behavioral effects overlap its other properties in rats. Psychopharmacology (Berl). 2002 Oct;164(1):93-107. Epub 2002 Jul 19. PubMed PMID: 12373423.