TargetMol

LY 97241

Product Code:
 
TAR-T27927
Product Group:
 
Inhibitors and Activators
Supplier:
 
TargetMol
Regulatory Status:
 
RUO
Shipping:
 
cool pack
Storage:
 
-20℃
1 / 1
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CodeSizePrice
TAR-T27927-5mg5mg£850.00
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TAR-T27927-50mg50mg£1,661.00
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Quantity:
TAR-T27927-100mg100mg£2,079.00
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This product comes from: United States.
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Further Information

Bioactivity:
LY 97241 is an inhibitor of hEAG1 and hERG1 potassium channel.
CAS:
72456-63-4
Formula:
C19H32N2O2
Molecular Weight:
320.477
Purity:
0.98
SMILES:
CCCCCCCN(CC)CCCCc1ccc(cc1)[N+]([O-])=O

References

1. Gessner G, Zacharias M, Bechstedt S, Sch?nherr R, Heinemann SH. Molecular determinants for high-affinity block of human EAG potassium channels by antiarrhythmic agents. Mol Pharmacol. 2004 May;65(5):1120-9. PubMed PMID: 15102940. 2. Gessner G, Heinemann SH. Inhibition of hEAG1 and hERG1 potassium channels by clofilium and its tertiary analogue LY97241. Br J Pharmacol. 2003 Jan;138(1):161-71. PubMed PMID: 12522086; PubMed Central PMCID: PMC1573651. 3. Finlayson K, Turnbull L, January CT, Sharkey J, Kelly JS. [3H]dofetilide binding to HERG transfected membranes: a potential high throughput preclinical screen. Eur J Pharmacol. 2001 Oct 26;430(1):147-8. PubMed PMID: 11698075. 4. Steidl JV, Yool AJ. Distinct mechanisms of block of Kv1.5 channels by tertiary and quaternary amine clofilium compounds. Biophys J. 2001 Nov;81(5):2606-13. PubMed PMID: 11606274; PubMed Central PMCID: PMC1301728.