TargetMol

LY2922083

Product Code:
 
TAR-T27938
Product Group:
 
Inhibitors and Activators
Supplier:
 
TargetMol
Regulatory Status:
 
RUO
Shipping:
 
cool pack
Storage:
 
-20℃
1 / 1
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CodeSizePrice
TAR-T27938-5mg5mg£1,010.00
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TAR-T27938-50mg50mg£1,982.00
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Quantity:
TAR-T27938-100mg100mg£2,560.00
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This product comes from: United States.
Typical lead time: 10-14 working days.
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Further Information

Bioactivity:
LY2922083 is a Potent and Selective GPR40 agonist. LY2922083 demonstrates potent, efficacious and durable dose dependent reductions in glucose levels along with significant increases in insulin and GLP-1 secretion.
CAS:
1309435-78-6
Formula:
C31H33NO3S
Molecular Weight:
499.67
Purity:
0.98
SMILES:
CC#C[C@@H](CC(O)=O)c1ccc(OCc2ccc(CN3CCC4(CCc5ccccc45)CC3)s2)cc1

References

1. Hamdouchi C, Kahl SD, Patel Lewis A, Cardona GR, Zink RW, Chen K, Eessalu TE, Ficorilli JV, Marcelo MC, Otto KA, Wilbur KL, Lineswala JP, Piper JL, Coffey DS, Sweetana SA, Haas JV, Brooks DA, Pratt EJ, Belin RM, Deeg MA, Ma X, Cannady EA, Johnson JT, Yumibe NP, Chen Q, Maiti P, Montrose-Rafizadeh C, Chen Y, Reifel Miller A. The Discovery, Preclinical and Early Clinical Development of Potent and Selective GPR40 Agonists for the Treatment of Type 2 Diabetes Mellitus (LY2881835, LY2922083 and LY2922470). J Med Chem. 2016 Oct 17. [Epub ahead of print] PubMed PMID: 27749056.