TargetMol

Ancremonam

Product Code:
 
TAR-T27962
Product Group:
 
Inhibitors and Activators
Supplier:
 
TargetMol
Regulatory Status:
 
RUO
Shipping:
 
cool pack
Storage:
 
-20℃
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TAR-T27962-5mg5mgEnquire
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Further Information

Bioactivity:
LYS228 is a potent antibiotics against Carbapenem-Resistant Enterobacteriaceae (MIC90 = 2 uM/mL). LYS228 is potent in the presence of all classes of beta-lactamases.
CAS:
1810051-96-7
Formula:
C16H18N6O10S2
Molecular Weight:
518.47
Purity:
0.98
SMILES:
Nc1nc(cs1)C(=NOC1(CC1)C(O)=O)C(=O)N[C@H]1[C@@H](CN2CCOC2=O)N(C1=O)S(O)(=O)=O

References

1. Klingen AR, Palsdottir H, Hunte C, Ullmann GM. Redox-linked protonation state changes in cytochrome bc1 identified by Poisson-Boltzmann electrostatics calculations. Biochim Biophys Acta. 2007 Mar;1767(3):204-21. Epub 2007 Jan 31. PubMed PMID: 17349966. 2. Rosell A, Valencia E, Ochoa WF, Fita I, Par?s X, Farr?s J. Complete reversal of coenzyme specificity by concerted mutation of three consecutive residues in alcohol dehydrogenase. J Biol Chem. 2003 Oct 17;278(42):40573-80. Epub 2003 Aug 4. PubMed PMID: 12902331. 3. Rosell A, Valencia E, Par?s X, Fita I, Farr?s J, Ochoa WF. Crystal structure of the vertebrate NADP(H)-dependent alcohol dehydrogenase (ADH8). J Mol Biol. 2003 Jun 27;330(1):75-85. PubMed PMID: 12818203. 4. Shimizu T, Nakatsu T, Miyairi K, Okuno T, Kato H. Active-site architecture of endopolygalacturonase I from Stereum purpureum revealed by crystal structures in native and ligand-bound forms at atomic resolution. Biochemistry. 2002 May 28;41(21):6651-9. PubMed PMID: 12022868.