TargetMol

MDK0734

Product Code:
 
TAR-T27989
Product Group:
 
Inhibitors and Activators
Supplier:
 
TargetMol
Regulatory Status:
 
RUO
Shipping:
 
cool pack
Storage:
 
-20℃
1 / 1
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CodeSizePrice
TAR-T27989-5mg5mg£850.00
Special offer! Add £1 to your order to get a TargetMol CCK-8 Kit. Read more here.
Quantity:
TAR-T27989-50mg50mg£1,661.00
Special offer! Add £1 to your order to get a TargetMol CCK-8 Kit. Read more here.
Quantity:
TAR-T27989-100mg100mg£2,079.00
Special offer! Add £1 to your order to get a TargetMol CCK-8 Kit. Read more here.
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This product comes from: United States.
Typical lead time: 10-14 working days.
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Further Information

Bioactivity:
MDK0734 is a selective inhibitor of cathepsin B endopeptidase and exopeptidase activities.
CAS:
1366240-73-4
Formula:
C15H17N3O2
Molecular Weight:
271.32
Purity:
0.98
SMILES:
CC1CCN(CC1)c1ccc([N+]([O-])=O)c2cccnc12

References

1. Chen H, Lv M, Lv Z, Li C, Zhang W, Zhao X, Duan X, Jin C, Xiong J, Xu F, Li Y. Divergent roles of three cytochrome c in CTSB-modulating coelomocyte apoptosis in Apostichopus japonicus. Dev Comp Immunol. 2017 May 24;76:65-76. doi: 10.1016/j.dci.2017.05.018. [Epub ahead of print] PubMed PMID: 28549733. 2. Li H, Wang F, Ge S, Liu H, Yan M, Yu J. Turning Nonspecific Interference into Signal Amplification: Covalent Biosensing Nanoassembly Enabled by Metal-Catalyzed Cross-Coupling. Anal Chem. 2017 May 26. doi: 10.1021/acs.analchem.7b01269. [Epub ahead of print] PubMed PMID: 28548821. 3. Xie X, Yi W, Zhang P, Wu N, Yan Q, Yang H, Tian C, Xiang S, Du M, Getachew Assefa E, Zuo X, Ying C. Green Tea Polyphenols, Mimicking the Effects of Dietary Restriction, Ameliorate High-Fat Diet-Induced Kidney Injury via Regulating Autophagy Flux. Nutrients. 2017 May 14;9(5). pii: E497. doi: 10.3390/nu9050497. PubMed PMID: 28505110. 4. Zhang X, Yang X, Wang H, Li S, Guo K, Jiang D, Xiao J, Liang D. Design, synthesis, and structure-activity relationship study of epoxysuccinyl-peptide derivatives as cathepsin B inhibitors. Biol Pharm Bull. 2017 May 13. doi: 10.1248/bpb.b17-00075. [Epub ahead of print] PubMed PMID: 28502922.