TargetMol

NCDM-32B

Product Code:
 
TAR-T28138
Product Group:
 
Inhibitors and Activators
Supplier:
 
TargetMol
Regulatory Status:
 
RUO
Shipping:
 
cool pack
Storage:
 
-20℃
1 / 1
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CodeSizePrice
TAR-T28138-5mg5mg£244.00
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TAR-T28138-50mg50mg£728.00
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Quantity:
TAR-T28138-100mg100mg£1,058.00
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This product comes from: United States.
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Further Information

Bioactivity:
NCDM-32B, a novel potent and selective KDM4 inhibitor, impairs viability and transforms phenotypes of basal breast cancer.
CAS:
1239468-48-4
Formula:
C15H30N2O4
Molecular Weight:
302.415
Purity:
0.98
SMILES:
COC(=O)CCN(O)C(=O)CCCCCCCCN(C)C

References

1. Ye Q, Holowatyj A, Wu J, Liu H, Zhang L, Suzuki T, Yang ZQ. Genetic alterations of KDM4 subfamily and therapeutic effect of novel demethylase inhibitor in breast cancer. Am J Cancer Res. 2015 Mar 15;5(4):1519-30. eCollection 2015. PubMed PMID: 26101715; PubMed Central PMCID: PMC4473328. 2. Inoue S, Moriya M, Watanabe Y, Miyagawa-Tomita S, Niihori T, Oba D, Ono M, Kure S, Ogura T, Matsubara Y, Aoki Y. New BRAF knockin mice provide a pathogenetic mechanism of developmental defects and a therapeutic approach in cardio-facio-cutaneous syndrome. Hum Mol Genet. 2014 Dec 15;23(24):6553-66. doi: 10.1093/hmg/ddu376. Epub 2014 Jul 17. PubMed PMID: 25035421.