TargetMol

NSC1011

Product Code:
 
TAR-T28201
Product Group:
 
Inhibitors and Activators
Supplier:
 
TargetMol
Regulatory Status:
 
RUO
Shipping:
 
cool pack
Storage:
 
-20℃
1 / 1
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CodeSizePrice
TAR-T28201-5mg5mg£850.00
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Quantity:
TAR-T28201-50mg50mg£1,661.00
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Quantity:
TAR-T28201-100mg100mg£2,079.00
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This product comes from: United States.
Typical lead time: 10-14 working days.
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Further Information

Bioactivity:
NSC1011 is an inhibitor of ras converting enzyme 1 (Rce1).
CAS:
5335-97-7
Formula:
C23H18N2O3
Molecular Weight:
370.408
Purity:
0.98
SMILES:
OC(=O)c1ccc(NC(c2ccccc2)c2ccc3cccnc3c2O)cc1

References

1. Mohammed I, Hampton SE, Ashall L, Hildebrandt ER, Kutlik RA, Manandhar SP, Floyd BJ, Smith HE, Dozier JK, Distefano MD, Schmidt WK, Dore TM. 8-Hydroxyquinoline-based inhibitors of the Rce1 protease disrupt Ras membrane localization in human cells. Bioorg Med Chem. 2016 Jan 15;24(2):160-78. doi: 10.1016/j.bmc.2015.11.043. Epub 2015 Nov 30. PubMed PMID: 26706114; PubMed Central PMCID: PMC4749511.