TargetMol

NVP-QAV-680

Product Code:
 
TAR-T28221
Product Group:
 
Inhibitors and Activators
Supplier:
 
TargetMol
Regulatory Status:
 
RUO
Shipping:
 
cool pack
Storage:
 
-20℃
1 / 1
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CodeSizePrice
TAR-T28221-5mg5mg£850.00
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Quantity:
TAR-T28221-50mg50mg£1,661.00
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Quantity:
TAR-T28221-100mg100mg£2,079.00
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This product comes from: United States.
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Further Information

Bioactivity:
NVP-QAV-680 is a potent and selective antagonist of CRTh2 receptor. NVP-QAV-680 has nM functional potency for inhibition of CRTh2 driven human eosinophil and Th2 lymphocyte activation in vitro.
CAS:
872365-16-7
Formula:
C18H18N2O4S
Molecular Weight:
358.41
Purity:
0.98
SMILES:
Cc1c(CC(O)=O)c2cccnc2n1Cc1ccc(cc1)S(C)(=O)=O

References

1. Sandham DA, Arnold N, Aschauer H,et al. Discovery and characterization of NVP-QAV680, a potent and selective CRTh2 receptor antagonist suitable for clinical testing in allergic diseases. Bioorg Med Chem. 2013 Nov 1;21(21):6582-91. doi: 10.1016/j.bmc.2013.08.025. Epub 2013 Aug 22. PubMed PMID: 24021582.