TargetMol

Ono-3805 sodium

Product Code:
 
TAR-T28249
Product Group:
 
Inhibitors and Activators
Supplier:
 
TargetMol
Regulatory Status:
 
RUO
Shipping:
 
cool pack
Storage:
 
-20℃
1 / 1
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CodeSizePrice
TAR-T28249-5mg5mg£850.00
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Further Information

Bioactivity:
Ono-3805 is an inhibitor of nonsteroidal 5 alpha-reductase.
CAS:
119347-91-0
Formula:
C31H36NNaO5
Molecular Weight:
525.621
Purity:
0.98
SMILES:
[Na+].CC(C)Cc1ccc(cc1)C(C)Oc1ccc(C(=O)Nc2ccccc2OCCCC([O-])=O)c(C)c1C

References

1. Aggarwal S, Thareja S, Verma A, Bhardwaj TR, Kumar M. An overview on 5alpha-reductase inhibitors. Steroids. 2010 Feb;75(2):109-53. doi: 10.1016/j.steroids.2009.10.005. Review. PubMed PMID: 19879888. 2. Igarashi S, Inami H, Hara H, Koutoku H, Oritani H, Mase T. A novel class of inhibitors for human and rat steroid 5alpha-reductases: synthesis and biological evaluation of indoline and aniline derivatives. III. Chem Pharm Bull (Tokyo). 2000 Nov;48(11):1689-97. PubMed PMID: 11086897. 3. Takami H, Nonaka H, Kishibayashi N, Ishii A, Kase H, Kumazawa T. Synthesis of tricyclic compounds as steroid 5alpha-reductase inhibitors. Chem Pharm Bull (Tokyo). 2000 Apr;48(4):552-5. PubMed PMID: 10783077. 4. Takami H, Koshimura H, Kishibayashi N, Ishii A, Nonaka H, Aoyama S, Kase H, Kumazawa T. Indole derivatives as a new class of steroid 5 alpha-reductase inhibitors. J Med Chem. 1996 Dec 20;39(26):5047-52. PubMed PMID: 8978835.