TargetMol

ORM-3819

Product Code:
 
TAR-T28268
Product Group:
 
Inhibitors and Activators
Supplier:
 
TargetMol
Regulatory Status:
 
RUO
Shipping:
 
cool pack
Storage:
 
-20℃
1 / 1
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CodeSizePrice
TAR-T28268-5mg5mg£850.00
Special offer! Add £1 to your order to get a TargetMol CCK-8 Kit. Read more here.
Quantity:
TAR-T28268-50mg50mg£1,661.00
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Quantity:
TAR-T28268-100mg100mg£2,079.00
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This product comes from: United States.
Typical lead time: 10-14 working days.
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Further Information

Bioactivity:
ORM-3819 is a potent and selective PDE III inhibitor. ORM-3819 promotes cardiac contractility through Ca(2+) sensitization.
CAS:
360794-85-0
Formula:
C19H19N5O5
Molecular Weight:
397.391
Purity:
0.98
SMILES:
COc1c(O)ccc(C=NNc2ccc(cc2)C2=NNC(=O)C[C@H]2C)c1[N+]([O-])=O

References

1. Nagy L, Pollesello P, Haikala H, V?gh ?, Sorsa T, Levijoki J, Szil?gyi S, ?des I, T?th A, Papp Z, Papp JG. ORM-3819 promotes cardiac contractility through Ca(2+) sensitization in combination with selective PDE III inhibition, a novel approach to inotropy. Eur J Pharmacol. 2016 Mar 15;775:120-9. doi: 10.1016/j.ejphar.2016.02.028. Epub 2016 Feb 9. PubMed PMID: 26872993.