TargetMol

Osemozotan HCl

Product Code:
 
TAR-T28270
Product Group:
 
Inhibitors and Activators
Supplier:
 
TargetMol
Regulatory Status:
 
RUO
Shipping:
 
cool pack
Storage:
 
-20℃
1 / 1
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CodeSizePrice
TAR-T28270-5mg5mg£1,010.00
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TAR-T28270-50mg50mg£1,982.00
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TAR-T28270-100mg100mg£2,560.00
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This product comes from: United States.
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Further Information

Bioactivity:
Osemozotan is a 5-HT1A receptor agonist potentially for the treatment of generalized anxiety disorder.
CAS:
137275-80-0
Formula:
C19H22ClNO5
Molecular Weight:
379.84
Purity:
0.98
SMILES:
Cl.C(CNC[C@H]1COc2ccccc2O1)COc1ccc2OCOc2c1

References

1. Matsuda T. Neuropharmacologic studies on the brain serotonin1A receptor using the selective agonist osemozotan. Biol Pharm Bull. 2013;36(12):1871-82. Review. PubMed PMID: 24292048. 2. Tsuchida R, Kubo M, Shintani N, Abe M, K?ves K, Uetsuki K, Kuroda M, Hashimoto H, Baba A. Inhibitory effects of osemozotan, a serotonin 1A-receptor agonist, on methamphetamine-induced c-Fos expression in prefrontal cortical neurons. Biol Pharm Bull. 2009 Apr;32(4):728-31. PubMed PMID: 19336914. 3. Tsuchida R, Kubo M, Kuroda M, Shibasaki Y, Shintani N, Abe M, K?ves K, Hashimoto H, Baba A. An antihyperkinetic action by the serotonin 1A-receptor agonist osemozotan co-administered with psychostimulants or the non-stimulant atomoxetine in mice. J Pharmacol Sci. 2009 Mar;109(3):396-402. Epub 2009 Mar 7. PubMed PMID: 19270432. 4. Ago Y, Nakamura S, Hayashi A, Itoh S, Baba A, Matsuda T. Effects of osemozotan, ritanserin and azasetron on cocaine-induced behavioral sensitization in mice. Pharmacol Biochem Behav. 2006 Sep;85(1):198-205. Epub 2006 Sep 8. PubMed PMID: 16962650.