TargetMol

OXA-11

Product Code:
 
TAR-T28277
Product Group:
 
Inhibitors and Activators
Supplier:
 
TargetMol
Regulatory Status:
 
RUO
Shipping:
 
cool pack
Storage:
 
-20℃
1 / 1
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CodeSizePrice
TAR-T28277-5mg5mg£1,572.00
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TAR-T28277-50mg50mg£3,107.00
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Quantity:
TAR-T28277-100mg100mg£4,247.00
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This product comes from: United States.
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  • Further Information
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Further Information

Bioactivity:
OXA-11 is a potent inhibitor of focal adhesion kinase (FAK) with anti-tumor activity.
CAS:
1257994-15-2
Formula:
C37H49F3N7O5P
Molecular Weight:
759.812
Purity:
0.98
SMILES:
CCOP(=O)(Cc1ccc(Nc2ncc(c(Nc3ccc([C@H]4CC[C@@H](CC4)N4CCN(C)CC4)c4CN(C)C(=O)c34)n2)C(F)(F)F)c(OC)c1)OCC

References

1. Moen I, Gebre M, Alonso-Camino V, Chen D, Epstein D, McDonald DM. Anti-metastatic action of FAK inhibitor OXA-11 in combination with VEGFR-2 signaling blockade in pancreatic neuroendocrine tumors. Clin Exp Metastasis. 2015 Dec;32(8):799-817. doi: 10.1007/s10585-015-9752-z. PubMed PMID: 26445848; PubMed Central PMCID: PMC4651821. 2. Anjum MF, Lemma F, Cork DJ, Meunier D, Murphy N, North SE, Woodford N, Haines J, Randall LP. Isolation and detection of extended spectrum ?-lactamase (ESBL)-producing enterobacteriaceae from meat using chromogenic agars and isothermal loop-mediated amplification (LAMP) assays. J Food Sci. 2013 Dec;78(12):M1892-8. doi: 10.1111/1750-3841.12297. PubMed PMID: 24329955. 3. Wang C, Cheng YQ. Thailandepsin a. Acta Crystallogr Sect E Struct Rep Online. 2011 Nov;67(Pt 11):o2948-9. doi: 10.1107/S1600536811041390. PubMed PMID: 22219976; PubMed Central PMCID: PMC3247358. 4. Yang D, Guo Y, Zhang Z. Combined porin loss and extended spectrum beta-lactamase production is associated with an increasing imipenem minimal inhibitory concentration in clinical Klebsiella pneumoniae strains. Curr Microbiol. 2009 Apr;58(4):366-70. doi: 10.1007/s00284-009-9364-4. PubMed PMID: 19219497.