TargetMol

Palinavir

Product Code:
 
TAR-T28292
Product Group:
 
Inhibitors and Activators
Supplier:
 
TargetMol
Regulatory Status:
 
RUO
Shipping:
 
cool pack
Storage:
 
-20℃
1 / 1
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CodeSizePrice
TAR-T28292-5mg5mg£1,091.00
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TAR-T28292-50mg50mg£2,143.00
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Quantity:
TAR-T28292-100mg100mg£2,801.00
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This product comes from: United States.
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  • Further Information
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Further Information

Bioactivity:
Palinavir is an antiviral, it inhibits HIV-1 protease.
CAS:
154612-39-2
Formula:
C41H52N6O5
Molecular Weight:
708.904
Purity:
0.98
SMILES:
CC(C)[C@H](NC(=O)c1ccc2ccccc2n1)C(=O)N[C@@H](Cc1ccccc1)[C@H](O)CN1CC[C@H](C[C@H]1C(=O)NC(C)(C)C)OCc1ccncc1

References

1. Lamarre D, Croteau G, Wardrop E, Bourgon L, Thibeault D, Clouette C, Vaillancourt M, Cohen E, Pargellis C, Yoakim C, Anderson PC. Antiviral properties of palinavir, a potent inhibitor of the human immunodeficiency virus type 1 protease. Antimicrob Agents Chemother. 1997 May;41(5):965-71. PubMed PMID: 9145853; PubMed Central PMCID: PMC163834. 2. Beaulieu PL, Anderson PC, Cameron DR, Croteau G, Gorys V, Grand-Ma?tre C, Lamarre D, Liard F, Paris W, Plamondon L, Soucy F, Thibeault D, Wernic D, Yoakim C, Pav S, Tong L. 2',6'-Dimethylphenoxyacetyl: a new achiral high affinity P(3)-P(2) ligand for peptidomimetic-based HIV protease inhibitors. J Med Chem. 2000 Mar 23;43(6):1094-108. PubMed PMID: 10737742. 3. Liard F, Jaramillo J, Paris WL, Yoakim C. Pharmacokinetic aspects of palinavir, an HIV protease inhibitor, in Sprague-Dawley rats. J Pharm Sci. 1998 Jun;87(6):782-5. PubMed PMID: 9607960. 4. Ohlmann T, Pr?v?t D, D?cimo D, Roux F, Garin J, Morley SJ, Darlix JL. In vitro cleavage of eIF4GI but not eIF4GII by HIV-1 protease and its effects on translation in the rabbit reticulocyte lysate system. J Mol Biol. 2002 Apr 19;318(1):9-20. PubMed PMID: 12054764.