TargetMol

PD 138142

Product Code:
 
TAR-T28332
Product Group:
 
Inhibitors and Activators
Supplier:
 
TargetMol
Regulatory Status:
 
RUO
Shipping:
 
cool pack
Storage:
 
-20℃
1 / 1
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CodeSizePrice
TAR-T28332-5mg5mg£850.00
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TAR-T28332-50mg50mg£1,661.00
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Quantity:
TAR-T28332-100mg100mg£2,079.00
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Further Information

Bioactivity:
PD 138142 is a water soluble inhibitor of ACAT.
CAS:
142642-31-7
Formula:
C25H35NO5S
Molecular Weight:
461.62
Purity:
0.98
SMILES:
CC(C)c1cccc(C(C)C)c1OC(=O)NS(=O)(=O)Oc1c(cccc1C(C)C)C(C)C

References

1. Carr TP, Hamilton RL Jr, Rudel LL. ACAT inhibitors decrease secretion of cholesteryl esters and apolipoprotein B by perfused livers of African green monkeys. J Lipid Res. 1995 Jan;36(1):25-36. PubMed PMID: 7706945. 2. Wolfgang GH, Robertson DG, Welty DF, Metz AL. Hepatic and adrenal toxicity of a novel lipid regulator in beagle dogs. Fundam Appl Toxicol. 1995 Jul;26(2):272-81. PubMed PMID: 7589916. 3. Robertson DG, Krause BR, Welty DF, Wolfgang GH, Graziano MJ, Pilcher GD, Urda E. Hepatic microsomal induction profile of carbamic acid [[2,6-bis(1- methylethyl)phenoxy] sulfonyl]-2,6-bis(1-methylethyl) phenyl ester, monosodium salt (PD138142-15), a novel lipid regulating agent. Biochem Pharmacol. 1995 Mar 15;49(6):799-808. PubMed PMID: 7702638. 4. Diczfalusy MA, Bj?rkhem I, Einarsson K, Alexson SE. Acyl-coenzyme A:cholesterol O-acyltransferase is not identical to liver microsomal carboxylesterase. Arterioscler Thromb Vasc Biol. 1996 Apr;16(4):606-10. PubMed PMID: 8624784.