TargetMol

PF-06456384

Product Code:
 
TAR-T28371
Product Group:
 
Inhibitors and Activators
Supplier:
 
TargetMol
Regulatory Status:
 
RUO
Shipping:
 
cool pack
Storage:
 
-20℃
1 / 1
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CodeSizePrice
TAR-T28371-5mg5mg£1,091.00
Special offer! Add £1 to your order to get a TargetMol CCK-8 Kit. Read more here.
Quantity:
TAR-T28371-50mg50mg£2,143.00
Special offer! Add £1 to your order to get a TargetMol CCK-8 Kit. Read more here.
Quantity:
TAR-T28371-100mg100mg£2,801.00
Special offer! Add £1 to your order to get a TargetMol CCK-8 Kit. Read more here.
Quantity:
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This product comes from: United States.
Typical lead time: 10-14 working days.
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Further Information

Bioactivity:
PF-06456384 is a highly potent and selective NaV1.7 inhibitor with IC50 value of 0.01 nM.
CAS:
1834610-73-9
Formula:
C35H32F3N7O3S2
Molecular Weight:
719.8
Purity:
0.98
SMILES:
FC(F)(F)c1cccc(c1)-c1ccc(Oc2ccc(cc2C#N)S(=O)(=O)Nc2ncns2)c(c1)-c1ccnc(CNCCC2CCNCC2)c1

References

1. Highly potent and selective NaV1.7 inhibitors for use as intravenous agents and chemical probes In Press, Accepted Manuscript, Available online 28 September 2017 R. Ian Storer, Andy Pike, Nigel A. Swain, Aristos J Alexandrou, Bruce M. Bechle, David C. Blakemore, Alan D. Brown, Neil A. Castle, Matthew S. Corbett, Neil J. Flanagan, David Fengas, M. Scott Johnson, Lyn H. Jones, Brian E. Marron, C. Elizabeth Payne, David Printzenhoff, David J. Rawson, Colin R. Rose, Thomas Ryckmans, Jianmin Sun, Jonathan W Theile, et al.