TargetMol

PNU-142731A HCl

Product Code:
 
TAR-T28433
Product Group:
 
Inhibitors and Activators
Supplier:
 
TargetMol
Regulatory Status:
 
RUO
Shipping:
 
cool pack
Storage:
 
-20℃
1 / 1
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CodeSizePrice
TAR-T28433-5mg5mg£930.00
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TAR-T28433-50mg50mg£1,821.00
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Quantity:
TAR-T28433-100mg100mg£2,319.00
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This product comes from: United States.
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Further Information

Bioactivity:
PNU-142731A HCl, a mediator release inhibitor and an IL-5 production inhibitor, is used potentially for the treatment of asthma.
CAS:
214212-38-1
Formula:
C24H31ClN6O
Molecular Weight:
455
Purity:
0.98
SMILES:
Cl.O=C(Cn1c2ccccc2c2c(nc(nc12)N1CCCC1)N1CCCC1)N1CCCC1

References

1. Dent G. PNU-142731A Pharmacia. Curr Opin Investig Drugs. 2000 Dec;1(4):449-51. Review. PubMed PMID: 11249698. 2. Chin JE, Hatfield CA, Winterrowd GE, Krzesicki RF, Shull KL, Fidler SF, Kolbasa KP, Brashler JR, Griffin RL, Fleming WE, Justen JM, Banitt LS, Bundy GL, Richards IM. Preclinical evaluation of anti-inflammatory activities of the novel pyrrolopyrimidine PNU-142731A, a potential treatment for asthma. J Pharmacol Exp Ther. 1999 Jul;290(1):188-95. PubMed PMID: 10381775.