TargetMol

PPZ2

Product Code:
 
TAR-T28445
Product Group:
 
Inhibitors and Activators
Supplier:
 
TargetMol
Regulatory Status:
 
RUO
Shipping:
 
cool pack
Storage:
 
-20℃
1 / 1
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CodeSizePrice
TAR-T28445-5mg5mg£850.00
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TAR-T28445-50mg50mg£1,661.00
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Quantity:
TAR-T28445-100mg100mg£2,079.00
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This product comes from: United States.
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Further Information

Bioactivity:
PPZ2 is a novel DAG-activated TRPC3/TRPC6/TRPC7 channels activator.
CAS:
896203-18-2
Formula:
C22H29N3O2
Molecular Weight:
367.49
Purity:
0.98
SMILES:
O=C(NC1=CC=CC=C1OCC)CN2CCN(C3=CC=CC(C)=C3C)CC2

References

1. Sawamura S, Hatano M, Takada Y, Hino K, Kawamura T, Tanikawa J, Nakagawa H, Hase H, Nakao A, Hirano M, Rotrattanadumrong R, Kiyonaka S, Mori MX, Nishida M, Hu Y, Inoue R, Nagata R, Mori Y. Screening of Transient Receptor Potential Canonical Channel Activators Identifies Novel Neurotrophic Piperazine Compounds. Mol Pharmacol. 2016 Mar;89(3):348-63. doi: 10.1124/mol.115.102863. Epub 2016 Jan 5. PubMed PMID: 26733543. 2. Cheng YL, Chen RH. Assembly and quality control of the protein phosphatase 1 holoenzyme involves the Cdc48-Shp1 chaperone. J Cell Sci. 2015 Mar 15;128(6):1180-92. doi: 10.1242/jcs.165159. Epub 2015 Jan 22. PubMed PMID: 25616896. 3. Merchan S, Pedelini L, Hueso G, Calzada A, Serrano R, Yenush L. Genetic alterations leading to increases in internal potassium concentrations are detrimental for DNA integrity in Saccharomyces cerevisiae. Genes Cells. 2011 Feb;16(2):152-65. doi: 10.1111/j.1365-2443.2010.01472.x. Epub 2010 Dec 9. PubMed PMID: 21143561. 4. Bozaquel-Morais BL, Madeira JB, Maya-Monteiro CM, Masuda CA, Montero-Lomeli M. A new fluorescence-based method identifies protein phosphatases regulating lipid droplet metabolism. PLoS One. 2010 Oct 28;5(10):e13692. doi: 10.1371/journal.pone.0013692. PubMed PMID: 21060891; PubMed Central PMCID: PMC2965658.