TargetMol

PR5-LL-CM01

Product Code:
 
TAR-T28448
Product Group:
 
Inhibitors and Activators
Supplier:
 
TargetMol
Regulatory Status:
 
RUO
Shipping:
 
cool pack
Storage:
 
-20℃
1 / 1
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Further Information

Bioactivity:
PR5-LL-CM01 is a novel protein arginine methyltransferase 5 (PRMT5) inhibitor in colorectal and pancreatic cancers.
CAS:
1005307-86-7
Formula:
C23H27N7
Molecular Weight:
401.518
Purity:
0.98
SMILES:
CN(C)CCNc1nc(Nc2ccc(C)c(C)c2)c2cnn(-c3ccccc3)c2n1

References

1. Prabhu L, Wei H, Chen L, Demir ?, Sandusky G, Sun E, Wang J, Mo J, Zeng L, Fishel M, Safa A, Amaro R, Korc M, Zhang ZY, Lu T. Adapting AlphaLISA high throughput screen to discover a novel small-molecule inhibitor targeting protein arginine methyltransferase 5 in pancreatic and colorectal cancers. Oncotarget. 2017 May 23. doi: 10.18632/oncotarget.18102. [Epub ahead of print] PubMed PMID: 28591716.