TargetMol

PT-262

Product Code:
 
TAR-T28469
Product Group:
 
Inhibitors and Activators
Supplier:
 
TargetMol
Regulatory Status:
 
RUO
Shipping:
 
cool pack
Storage:
 
-20℃
1 / 1
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Further Information

Bioactivity:
PT-262 is a ROCK (Rho-associated coiled-coil forming protein kinase) inhibitor. It induces cytoskeleton remodeling and migration inhibition in lung carcinoma cells.
CAS:
86811-36-1
Formula:
C14H13ClN2O2
Molecular Weight:
276.72
Purity:
0.98
SMILES:
ClC1=C(N2CCCCC2)C(=O)c2cccnc2C1=O

References

1. Tsai CC, Liu HF, Hsu KC, Yang JM, Chen C, Liu KK, Hsu TS, Chao JI. 7-Chloro-6-piperidin-1-yl-quinoline-5,8-dione (PT-262), a novel ROCK inhibitor blocks cytoskeleton function and cell migration. Biochem Pharmacol. 2011 Apr 1;81(7):856-65. doi: 10.1016/j.bcp.2011.01.009. Epub 2011 Jan 26. PubMed PMID: 21276421.