TargetMol

Racivir

Product Code:
 
TAR-T28499
Product Group:
 
Inhibitors and Activators
Supplier:
 
TargetMol
Regulatory Status:
 
RUO
Shipping:
 
cool pack
Storage:
 
-20℃
1 / 1
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CodeSizePrice
TAR-T28499-5mg5mg£850.00
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Quantity:
TAR-T28499-50mg50mg£1,661.00
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Quantity:
TAR-T28499-100mg100mg£2,079.00
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This product comes from: United States.
Typical lead time: 10-14 working days.
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Further Information

Bioactivity:
Racivir is a reverse transcriptase inhibitor. Racivir is anabolized to the active 5'-triphosphate in cells. HBV replication is equally inhibited in cultures incubated with Racivir when the compound is added 24 h preinfection, at infection, or 24 h postinfection. Racivir inhibits HBV replication by 50% at less than 20 nM in human hepatocytes.
CAS:
143491-54-7
Formula:
C8H10FN3O3S
Molecular Weight:
247.24
Purity:
0.98
SMILES:
Nc1nc(=O)n(cc1F)[C@H]1CS[C@@H](CO)O1

References

1. Amancha PK, Hong JJ, Rogers K, Ansari AA, Villinger F. In vivo blockade of the programmed cell death-1 pathway using soluble recombinant PD-1-Fc enhances CD4+ and CD8+ T cell responses but has limited clinical benefit. J Immunol. 2013 Dec 15;191(12):6060-70. doi: 10.4049/jimmunol.1302044. PubMed PMID: 24227774; PubMed Central PMCID: PMC3858463. 2. Ghosh RK, Ghosh SM, Chawla S. Recent advances in antiretroviral drugs. Expert Opin Pharmacother. 2011 Jan;12(1):31-46. doi: 10.1517/14656566.2010.509345. Review. PubMed PMID: 20698725. 3. Kohler JJ, Hosseini SH, Cucoranu I, Zhelyabovska O, Green E, Ivey K, Abuin A, Fields E, Hoying A, Russ R, Santoianni R, Raper CM, Yang Q, Lavie A, Lewis W. Transgenic cardiac-targeted overexpression of human thymidylate kinase. Lab Invest. 2010 Mar;90(3):383-90. doi: 10.1038/labinvest.2009.146. PubMed PMID: 20065942; PubMed Central PMCID: PMC2829097. 4. Verhoeven D, Sankaran S, Dandekar S. Simian immunodeficiency virus infection induces severe loss of intestinal central memory T cells which impairs CD4+ T-cell restoration during antiretroviral therapy. J Med Primatol. 2007 Aug;36(4-5):219-27. PubMed PMID: 17669210.