TargetMol

SC-68376

Product Code:
 
TAR-T28702
Product Group:
 
Inhibitors and Activators
Supplier:
 
TargetMol
Regulatory Status:
 
RUO
Shipping:
 
cool pack
Storage:
 
-20℃
1 / 1
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CodeSizePrice
TAR-T28702-5mg5mg£850.00
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This product comes from: United States.
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Further Information

Bioactivity:
SC-68376 is a potent, reversible, cell-permeable, ATP-competitive, and selective inhibitor of p38 MAP kinase.
CAS:
318480-82-9
Formula:
C15H12N2O
Molecular Weight:
236.274
Purity:
0.98
SMILES:
Cc1nc(c(o1)-c1ccncc1)-c1ccccc1

References

1. Kooijman R, Coppens A, Hooghe-Peters E. IGF-I stimulates IL-8 production in the promyelocytic cell line HL-60 through activation of extracellular signal-regulated protein kinase. Cell Signal. 2003 Dec;15(12):1091-8. PubMed PMID: 14575864. 2. Ermert M, Kuttner D, Eisenhardt N, Dierkes C, Seeger W, Ermert L. Cyclooxygenase-2-dependent and thromboxane-dependent vascular and bronchial responses are regulated via p38 mitogen-activated protein kinase in control and endotoxin-primed rat lungs. Lab Invest. 2003 Mar;83(3):333-47. PubMed PMID: 12649334.