TargetMol

Selenazofurin

Product Code:
 
TAR-T28744
Product Group:
 
Inhibitors and Activators
Supplier:
 
TargetMol
Regulatory Status:
 
RUO
Shipping:
 
cool pack
Storage:
 
-20℃
1 / 1
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CodeSizePrice
TAR-T28744-5mg5mg£930.00
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TAR-T28744-50mg50mg£1,821.00
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Quantity:
TAR-T28744-100mg100mg£2,319.00
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This product comes from: United States.
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Further Information

Bioactivity:
Selenazofurin is an antiviral compound. Selenazofurin inhibits the cytopathic effect and yield of influenza A/NWS/33 virus with 50% effective dose ranges of 0.7 to 1.4 micrograms/ml.
CAS:
83705-13-9
Formula:
C9H12N2O5Se
Molecular Weight:
307.175
Purity:
0.98
SMILES:
NC(=O)c1c[se]c(n1)[C@@H]1O[C@H](CO)[C@@H](O)[C@H]1O

References

1. Pogrebniak A, Hasmann M, Schemainda I, Pelka-Fleischer R, Nuessler V. Cytoprotective features of selenazofurin in hematopoietic cells. Int J Clin Pharmacol Ther. 2002 Aug;40(8):368-75. PubMed PMID: 12467305. 2. Franchetti P, Cappellacci L, Sheikha GA, Jayaram HN, Gurudutt VV, Sint T, Schneider BP, Jones WD, Goldstein BM, Perra G, De Montis A, Loi AG, La Colla P, Grifantini M. Synthesis, structure, and antiproliferative activity of selenophenfurin, an inosine 5'-monophosphate dehydrogenase inhibitor analogue of selenazofurin. J Med Chem. 1997 May 23;40(11):1731-7. PubMed PMID: 9171883. 3. Gharehbaghi K, Sreenath A, Hao Z, Paull KD, Szekeres T, Cooney DA, Krohn K, Jayaram HN. Comparison of biochemical parameters of benzamide riboside, a new inhibitor of IMP dehydrogenase, with tiazofurin and selenazofurin. Biochem Pharmacol. 1994 Oct 7;48(7):1413-9. PubMed PMID: 7945441. 4. Smee DF, Gilbert J, Leonhardt JA, Barnett BB, Huggins JH, Sidwell RW. Treatment of lethal Pichinde virus infections in weanling LVG/Lak hamsters with ribavirin, ribamidine, selenazofurin, and ampligen. Antiviral Res. 1993 Jan;20(1):57-70. PubMed PMID: 8384433.