TargetMol

Sezolamide hydrochloride

Product Code:
 
TAR-T28763
Product Group:
 
Inhibitors and Activators
Supplier:
 
TargetMol
Regulatory Status:
 
RUO
Shipping:
 
cool pack
Storage:
 
-20℃
1 / 1
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CodeSizePrice
TAR-T28763-5mg5mg£1,091.00
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TAR-T28763-50mg50mg£2,143.00
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Quantity:
TAR-T28763-100mg100mg£2,801.00
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This product comes from: United States.
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Further Information

Bioactivity:
Sezolamide hydrochloride is a potent topical carbonic anhydrase inhibitor.
CAS:
119271-78-2
Formula:
C11H19ClN2O4S3
Molecular Weight:
374.91
Purity:
0.98
SMILES:
Cl.CC(C)CN[C@H]1CCS(=O)(=O)c2sc(cc12)S(N)(=O)=O

References

1. Gunning FP, Greve EL, Bron AM, Bosc JM, Royer JG, George JL, Lesure P, Sirbat D. Two topical carbonic anhydrase inhibitors sezolamide and dorzolamide in Gelrite vehicle: a multiple-dose efficacy study. Graefes Arch Clin Exp Ophthalmol. 1993 Jul;231(7):384-8. PubMed PMID: 8406063. 2. Gunning F, B?chetoille A, Lippa EA, Pfeiffer N, Gerling J, Holder D, Clineschmidt C, Buntinx A, Brunner-Ferber FL, Grehn F, et al. Sezolamide: additivity to timolol twice daily. Eye (Lond). 1992;6 ( Pt 5):525-9. PubMed PMID: 1286720. 3. Buclin T, Biollaz J, Lippa EA, Brunner-Ferber F, van Melle G, Munafo A, Clineschmidt C, Schelling JL. Absence of metabolic effects of the topical carbonic anhydrase inhibitors MK-927 and sezolamide during two-week ocular administration to normal subjects. Clin Pharmacol Ther. 1991 Jun;49(6):665-73. PubMed PMID: 2060255. 4. Lippa EA, Schuman JS, Higginbotham EJ, Kass MA, Weinreb RN, Skuta GL, Epstein DL, Shaw B, Holder DJ, Deasy DA, et al. MK-507 versus sezolamide. Comparative efficacy of two topically active carbonic anhydrase inhibitors. Ophthalmology. 1991 Mar;98(3):308-12; discussion 312-3. PubMed PMID: 2023750.