TargetMol

SPV106

Product Code:
 
TAR-T28840
Product Group:
 
Inhibitors and Activators
Supplier:
 
TargetMol
Regulatory Status:
 
RUO
Shipping:
 
cool pack
Storage:
 
-20℃
1 / 1
❮❯

No additional charges, what you see is what you pay! *

CodeSizePrice
TAR-T28840-5mg5mg£850.00
Special offer! Add £1 to your order to get a TargetMol CCK-8 Kit. Read more here.
Quantity:
TAR-T28840-50mg50mg£1,661.00
Special offer! Add £1 to your order to get a TargetMol CCK-8 Kit. Read more here.
Quantity:
TAR-T28840-100mg100mg£2,079.00
Special offer! Add £1 to your order to get a TargetMol CCK-8 Kit. Read more here.
Quantity:
Prices exclude any Taxes / VAT
How to order with us   Contact us
Stay in control of your spending. These prices have no additional charges, not even shipping!
* Rare exceptions are clearly labelled (only 0.14% of items!).
Multibuy discounts available! Contact us to find what you can save.
This product comes from: United States.
Typical lead time: 10-14 working days.
Contact us for more accurate information.
  • Further Information
  • Documents
  • References
  • Show All

Further Information

Bioactivity:
SPV106 is a ligand of lysine acetyltransferases (KATs).
CAS:
1036939-38-4
Formula:
C18H30O4
Molecular Weight:
310.435
Purity:
0.98
SMILES:
CCCCCCCCCCCCCCC=C(C([O-])=O)C([O-])=O

References

1. Castellano S, Milite C, Feoli A, Viviano M, Mai A, Novellino E, Tosco A, Sbardella G. Identification of structural features of 2-alkylidene-1,3-dicarbonyl derivatives that induce inhibition and/or activation of histone acetyltransferases KAT3B/p300 and KAT2B/PCAF. ChemMedChem. 2015 Jan;10(1):144-57. doi: 10.1002/cmdc.201402371. Epub 2014 Oct 21. PubMed PMID: 25333655. 2. Cesselli D, Beltrami AP. Stem cell senescence in diabetes: forgetting the sweet old memories. Diabetes. 2014 Jun;63(6):1841-3. doi: 10.2337/db14-0275. PubMed PMID: 24853898. 3. Vecellio M, Spallotta F, Nanni S, Colussi C, Cencioni C, Derlet A, Bassetti B, Tilenni M, Carena MC, Farsetti A, Sbardella G, Castellano S, Mai A, Martelli F, Pompilio G, Capogrossi MC, Rossini A, Dimmeler S, Zeiher A, Gaetano C. The histone acetylase activator pentadecylidenemalonate 1b rescues proliferation and differentiation in the human cardiac mesenchymal cells of type 2 diabetic patients. Diabetes. 2014 Jun;63(6):2132-47. doi: 10.2337/db13-0731. Epub 2014 Jan 23. PubMed PMID: 24458358. 4. Spallotta F, Cencioni C, Straino S, Sbardella G, Castellano S, Capogrossi MC, Martelli F, Gaetano C. Enhancement of lysine acetylation accelerates wound repair. Commun Integr Biol. 2013 Sep 1;6(5):e25466. doi: 10.4161/cib.25466. Epub 2013 Jul 2. PubMed PMID: 24265859; PubMed Central PMCID: PMC3829946.