TargetMol

ST-148

Product Code:
 
TAR-T28860
Product Group:
 
Inhibitors and Activators
Supplier:
 
TargetMol
Regulatory Status:
 
RUO
Shipping:
 
cool pack
Storage:
 
-20℃
1 / 1
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CodeSizePrice
TAR-T28860-5mg5mg£850.00
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Quantity:
TAR-T28860-50mg50mg£1,661.00
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Quantity:
TAR-T28860-100mg100mg£2,079.00
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This product comes from: United States.
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Further Information

Bioactivity:
ST-148 is a potent inhibitor for Dengue virus capsid. ST-148-enhanced capsid protein self-interaction perturbs assembly and disassembly of DV nucleocapsids, probably by inducing structural rigidity.
CAS:
400863-77-6
Formula:
C21H19N5OS2
Molecular Weight:
421.54
Purity:
0.98
SMILES:
Nc1c(sc2nc3CCCCCc3cc12)C(=O)Nc1nnc(s1)-c1ccccc1

References

1. Finkelman MD, Jamison RN, Kulich RJ, Butler SF, Jackson WC, Smits N, Weiner SG. Cross-validation of short forms of the Screener and Opioid Assessment for Patients with Pain-Revised (SOAPP-R). Drug Alcohol Depend. 2017 Sep 1;178:94-100. doi: 10.1016/j.drugalcdep.2017.04.016. Epub 2017 Jun 13. PubMed PMID: 28645065. 2. Scaturro P, Trist IM, Paul D, Kumar A, Acosta EG, Byrd CM, Jordan R, Brancale A, Bartenschlager R. Characterization of the mode of action of a potent dengue virus capsid inhibitor. J Virol. 2014 Oct;88(19):11540-55. doi: 10.1128/JVI.01745-14. Epub 2014 Jul 23. PubMed PMID: 25056895; PubMed Central PMCID: PMC4178822. 3. Byrd CM, Dai D, Grosenbach DW, Berhanu A, Jones KF, Cardwell KB, Schneider C, Wineinger KA, Page JM, Harver C, Stavale E, Tyavanagimatt S, Stone MA, Bartenschlager R, Scaturro P, Hruby DE, Jordan R. A novel inhibitor of dengue virus replication that targets the capsid protein. Antimicrob Agents Chemother. 2013 Jan;57(1):15-25. doi: 10.1128/AAC.01429-12. Epub 2012 Oct 15. PubMed PMID: 23070172; PubMed Central PMCID: PMC3535982. 4. Weber B, Schlicker E, Sokoloff P, Stark H. Identification of the dopamine autoreceptor in the guinea-pig retina as D(2) receptor using novel subtype-selective antagonists. Br J Pharmacol. 2001 Aug;133(8):1243-8. PubMed PMID: 11498509; PubMed Central PMCID: PMC1621144.