TargetMol

Stemazole

Product Code:
 
TAR-T28866
Product Group:
 
Inhibitors and Activators
Supplier:
 
TargetMol
Regulatory Status:
 
RUO
Shipping:
 
cool pack
Storage:
 
-20℃
1 / 1
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CodeSizePrice
TAR-T28866-1mg1mg£155.00
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TAR-T28866-1mL1 mL * 10 mM (in DMSO)£254.00
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TAR-T28866-5mg5mg£269.00
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TAR-T28866-10mg10mg£389.00
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TAR-T28866-25mg25mg£744.00
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TAR-T28866-50mg50mg£1,139.00
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TAR-T28866-100mg100mg£1,805.00
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TAR-T28866-500mg500mg£3,548.00
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This product comes from: United States.
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Further Information

Bioactivity:
Stemazole, a human stem/progenitor cell proliferation activator, has been shown to promote survival and preserve stemness in human embryonic stem cells.
CAS:
317337-07-8
Formula:
C9H9N5OS2
Molecular Weight:
267.33
Pathway:
Apoptosis
Purity:
0.98
SMILES:
NNC(=S)Nc1ccc(cc1)-c1nnc(S)o1
Target:
Apoptosis

References

1. Sun Y, Zhang X, Li H, Xu S, Zhang X, Liu Y, Han M, Wen J. Stemazole promotes survival and preserves stemness in human embryonic stem cells. FEBS J. 2017 Dec 8. doi: 10.1111/febs.14355. [Epub ahead of print] PubMed PMID: 29222853. 2. Guo Z, Xu S, Du N, Liu J, Huang Y, Han M. Neuroprotective effects of stemazole in the MPTP-induced acute model of Parkinson's disease: Involvement of the dopamine system. Neurosci Lett. 2016 Mar 11;616:152-9. doi: 10.1016/j.neulet.2016.01.048. Epub 2016 Jan 28. PubMed PMID: 26827716. 3. Sun Y, Wang W, Sun Y, Han M. Synthesis and biological evaluation of a novel human stem/progenitor cells proliferation activator: 4-(4-(5-mercapto-1,3,4-oxadiazol-2-yl)phenyl) thiosemicarbazide (Stemazole). Eur J Med Chem. 2011 Jul;46(7):2930-6. doi: 10.1016/j.ejmech.2011.04.017. Epub 2011 Apr 12. PubMed PMID: 21531486. 4. Han M, Liu Y, Tan Q, Zhang B, Wang W, Liu J, Zhang XJ, Wang YY, Zhang JM. Therapeutic efficacy of stemazole in a beta-amyloid injection rat model of Alzheimer's disease. Eur J Pharmacol. 2011 Apr 25;657(1-3):104-10. doi: 10.1016/j.ejphar.2011.01.065. Epub 2011 Feb 17. PubMed PMID: 21316359.