TargetMol

T145

Product Code:
 
TAR-T28898
Product Group:
 
Inhibitors and Activators
Supplier:
 
TargetMol
Regulatory Status:
 
RUO
Shipping:
 
cool pack
Storage:
 
-20℃
1 / 1
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CodeSizePrice
TAR-T28898-5mg5mg£1,091.00
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Quantity:
TAR-T28898-50mg50mg£2,143.00
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Quantity:
TAR-T28898-100mg100mg£2,801.00
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Quantity:
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This product comes from: United States.
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Further Information

Bioactivity:
T145 inhibits growth of Enterococcus faecalis, Staphylococcus aureus and Mycobacterium tuberculosis (Mtb) with sub μg/ml potencies that are potentially therapeutically valuable. T145 minimizes selection of spontaneous resistant mutants, a trait that prolongs longevity of a drug in clinical use.
CAS:
1021186-98-0
Formula:
C18H16N2O5
Molecular Weight:
340.335
Purity:
0.98
SMILES:
CC(=O)NC[C@H]1CN(C(=O)O1)c1ccc2Oc3ccccc3Oc2c1

References

1. Kaushik A, Heuer AM, Bell DT, Culhane JC, Ebner DC, Parrish N, Ippoliti JT, Lamichhane G. An evolved oxazolidinone with selective potency against Mycobacterium tuberculosis and gram positive bacteria. Bioorg Med Chem Lett. 2016 Aug 1;26(15):3572-6. doi: 10.1016/j.bmcl.2016.06.019. Epub 2016 Jun 9. PubMed PMID: 27329794; PubMed Central PMCID: PMC4955536.