TargetMol

TA-606

Product Code:
 
TAR-T28908
Product Group:
 
Inhibitors and Activators
Supplier:
 
TargetMol
Regulatory Status:
 
RUO
Shipping:
 
cool pack
Storage:
 
-20℃
1 / 1
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CodeSizePrice
TAR-T28908-5mg5mg£1,171.00
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TAR-T28908-50mg50mg£2,303.00
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Quantity:
TAR-T28908-100mg100mg£3,042.00
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This product comes from: United States.
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  • Further Information
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Further Information

Bioactivity:
TA-606 is an angiotensin type 1 receptor antagonist with antihypertensive activity.
CAS:
190602-72-3
Formula:
C33H40ClN7O6
Molecular Weight:
666.18
Purity:
0.98
SMILES:
Cl.CCCc1nc2CCN(C(C(=O)OCOC(=O)OC(CC)CC)c2n1Cc1ccc(cc1)-c1ccccc1-c1nnn[nH]1)C(C)=O

References

1. Fukuda D, Enomoto S, Nagai R, Sata M. Inhibition of renin-angiotensin system attenuates periadventitial inflammation and reduces atherosclerotic lesion formation. Biomed Pharmacother. 2009 Dec;63(10):754-61. doi: 10.1016/j.biopha.2009.02.006. PubMed PMID: 19304450. 2. Kashimura T, Hayashi M, Kodama M, Nakazawa M, Abe S, Yoshida T, Tachikawa H, Hanawa H, Kato K, Watanabe K, Aizawa Y. Effects of imidapril and TA-606 on rat dilated cardiomyopathy after myocarditis. Jpn Heart J. 2003 Sep;44(5):735-44. PubMed PMID: 14587655. 3. Ishizaka N, Nakao A, Ohishi N, Suzuki M, Aizawa T, Taguchi J, Nagai R, Shimizu T, Ohno M. Increased leukotriene A(4) hydrolase expression in the heart of angiotensin II-induced hypertensive rat. FEBS Lett. 1999 Dec 10;463(1-2):155-9. PubMed PMID: 10601658. 4. Hashimoto Y, Ohashi R, Minami K, Narita H. Comparative study of TA-606, a novel angiotensin II receptor antagonist, with losartan in terms of species difference and orthostatic hypotension. Jpn J Pharmacol. 1999 Sep;81(1):63-72. PubMed PMID: 10580372.