TargetMol

Tomopenem

Product Code:
 
TAR-T28992
Product Group:
 
Inhibitors and Activators
Supplier:
 
TargetMol
Regulatory Status:
 
RUO
Shipping:
 
cool pack
Storage:
 
-20℃
1 / 1
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TAR-T28992-5mg5mg£850.00
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Further Information

Bioactivity:
Tomopenem is a penem antibiotic.
CAS:
222400-20-6
Formula:
C23H35N7O6S
Molecular Weight:
537.64
Purity:
0.98
SMILES:
O=C(C(N12)=C(S[C@@H]3CN(C)[C@H](C(N4C[C@@H](NC(CNC(N)=N)=O)CC4)=O)C3)[C@H](C)[C@]2([H])[C@@H]([C@H](O)C)C1=O)O

References

1. Ansari MA, Shaikh S, Shakil S, Rizvi SM. An enzoinformatics study for prediction of efficacies of three novel penem antibiotics against New Delhi metallo-?-lactamase-1 bacterial enzyme. Interdiscip Sci. 2014 Sep;6(3):208-15. doi: 10.1007/s12539-013-0202-9. PubMed PMID: 25205498. 2. Ansari MA, Shaikh S, Shakil S, Rizvi SM. An enzoinformatics study for prediction of efficacies of three novel penem antibiotics against New Delhi metallo-?-lactamase-1 bacterial enzyme. Interdiscip Sci. 2014 Aug 9. [Epub ahead of print] PubMed PMID: 25118651. 3. Sugihara K, Tateda K, Yamamura N, Koga T, Sugihara C, Yamaguchi K. Efficacy of human-simulated exposures of tomopenem (formerly CS-023) in a murine model of Pseudomonas aeruginosa and methicillin-resistant Staphylococcus aureus infection. Antimicrob Agents Chemother. 2011 Nov;55(11):5004-9. doi: 10.1128/AAC.00068-11. PubMed PMID: 21844314; PubMed Central PMCID: PMC3195026. 4. Sugihara K, Sugihara C, Matsushita Y, Yamamura N, Uemori M, Tokumitsu A, Inoue H, Kakuta M, Namba E, Nasu H, Koga T. In vivo pharmacodynamic activity of tomopenem (formerly CS-023) against Pseudomonas aeruginosa and methicillin-resistant Staphylococcus aureus in a murine thigh infection model. Antimicrob Agents Chemother. 2010 Dec;54(12):5298-302. doi: 10.1128/AAC.00267-10. PubMed PMID: 20921311; PubMed Central PMCID: PMC2981229.