TargetMol

UR-3216

Product Code:
 
TAR-T29074
Product Group:
 
Inhibitors and Activators
Supplier:
 
TargetMol
Regulatory Status:
 
RUO
Shipping:
 
cool pack
Storage:
 
-20℃
1 / 1
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CodeSizePrice
TAR-T29074-5mg5mg£850.00
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TAR-T29074-50mg50mg£1,661.00
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Quantity:
TAR-T29074-100mg100mg£2,079.00
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This product comes from: United States.
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Further Information

Bioactivity:
UR-3216, a prodrug, is a selective and orally active platelet surface glycoprotein (GPIIb/IIIa) receptor antagonist. UR-3216 is the very tight binding of its active metabolite to platelets (Ki for resting platelets is < 1 nM). UR-2992, the active form of UR-3216, binds to platelets for a long period of time, while the unbound drug is rapidly cleared.
CAS:
220386-65-2
Formula:
C27H29N7O7
Molecular Weight:
563.571
Purity:
0.98
SMILES:
CCOC(=O)Cn1cc2CN(CCc2n1)C(=O)[C@H](Cc1ccc(cc1)[N+]([O-])=O)NC(=O)c1ccc(cc1)C(N)=NO

References

1. Aga Y, Baba K, Tam S, Nakanishi T, Yoneda K, Kita J, Ueno H. UR-3216: a new generation oral platelet GPIIb/IIIa antagonist. Curr Pharm Des. 2004;10(14):1597-601. Review. PubMed PMID: 15134558. 2. Baba K, Aga Y, Nakanishi T, Motoyama T, Ueno H. UR-3216: a manageable oral GPIIb/IIIa antagonist. Cardiovasc Drug Rev. 2001 Spring;19(1):25-40. Review. PubMed PMID: 11314599.