TargetMol

VPC32183

Product Code:
 
TAR-T29113
Product Group:
 
Inhibitors and Activators
Supplier:
 
TargetMol
Regulatory Status:
 
RUO
Shipping:
 
cool pack
Storage:
 
-20℃
1 / 1

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CodeSizePrice
TAR-T29113-5mg5mg£1,010.00
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Quantity:
TAR-T29113-50mg50mg£1,982.00
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Quantity:
TAR-T29113-100mg100mg£2,560.00
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Quantity:
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This product comes from: United States.
Typical lead time: 10-14 working days.
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Further Information

Bioactivity:
VPC32183 is a competitive antagonist of LPA1 and LPA3 receptors.
CAS:
717110-61-7
Formula:
C33H51N2O6P
Molecular Weight:
602.753
Purity:
0.98
SMILES:
CCCCCCCCC=C/CCCCCCCC(=O)N[C@@H](COP(O)(O)=O)Cc1ccc(OCc2cccnc2)cc1

References

1. Violet PC, Billon-Denis E, Robin P. Inhibition of lipid phosphate phosphatase activity by VPC32183 suppresses the ability of diacylglycerol pyrophosphate to activate ERK(1/2) MAP kinases. Biochim Biophys Acta. 2012 Nov;1821(11):1394-405. doi: 10.1016/j.bbalip.2012.07.009. Epub 2012 Jul 20. PubMed PMID: 22820196. 2. Kim K, Kim HL, Lee YK, Han M, Sacket SJ, Jo JY, Kim YL, Im DS. Lysophosphatidylserine induces calcium signaling through Ki16425/VPC32183-sensitive GPCR in bone marrow-derived mast cells and in C6 glioma and colon cancer cells. Arch Pharm Res. 2008 Mar;31(3):310-7. doi: 10.1007/s12272-001-1157-x. Epub 2008 Apr 13. PubMed PMID: 18409043.