TargetMol

XC-302 free base

Product Code:
 
TAR-T29165
Product Group:
 
Inhibitors and Activators
Supplier:
 
TargetMol
Regulatory Status:
 
RUO
Shipping:
 
cool pack
Storage:
 
-20℃
1 / 1
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CodeSizePrice
TAR-T29165-5mg5mg£850.00
Special offer! Add £1 to your order to get a TargetMol CCK-8 Kit. Read more here.
Quantity:
TAR-T29165-50mg50mg£1,661.00
Special offer! Add £1 to your order to get a TargetMol CCK-8 Kit. Read more here.
Quantity:
TAR-T29165-100mg100mg£2,079.00
Special offer! Add £1 to your order to get a TargetMol CCK-8 Kit. Read more here.
Quantity:
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This product comes from: United States.
Typical lead time: 10-14 working days.
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Further Information

Bioactivity:
XC-302 is a multi-targeted inhibitor, it induces autophagy of nasopharyngeal cancer cells via inhibiting the PI3K/AKT/mTOR signaling pathway.
CAS:
916890-10-3
Formula:
C17H15N7
Molecular Weight:
317.356
Purity:
0.98
SMILES:
C1CC1Nc1nc(Nc2ccc3ncccc3c2)nc2[nH]cnc12

References

1. Wang KF, Yang H, Jiang WQ, Li S, Cai YC. Puquitinib mesylate (XC-302) induces autophagy via inhibiting the PI3K/AKT/mTOR signaling pathway in nasopharyngeal cancer cells. Int J Mol Med. 2015 Dec;36(6):1556-62. doi: 10.3892/ijmm.2015.2378. PubMed PMID: 26499488; PubMed Central PMCID: PMC4678157. 2. Yang H, Wang Y, Zhan J, Xia Y, Sun P, Bi XW, Liu PP, Li ZM, Li S, Zou BY, Jiang WQ. Puquitinib mesylate, an inhibitor of phosphatidylinositol 3-kinase p110?, for treating relapsed or refractory non-Hodgkin's lymphoma. Oncotarget. 2015 Dec 22;6(41):44049-56. doi: 10.18632/oncotarget.5833. PubMed PMID: 26510909; PubMed Central PMCID: PMC4791286.