TargetMol

YM-75466

Product Code:
 
TAR-T29190
Product Group:
 
Inhibitors and Activators
Supplier:
 
TargetMol
Regulatory Status:
 
RUO
Shipping:
 
cool pack
Storage:
 
-20℃
1 / 1
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CodeSizePrice
TAR-T29190-5mg5mg£850.00
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TAR-T29190-50mg50mg£1,661.00
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Quantity:
TAR-T29190-100mg100mg£2,079.00
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This product comes from: United States.
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Further Information

Bioactivity:
YM-75466 is a factor Xa inhibitor. YM-75466 did not prolong coagulation time even at the dose which exerted significant antithrombotic effects, while it decreased TAT level in plasma in a dose-dependent manner.
CAS:
209187-02-0
Formula:
C28H35N5O8S2
Molecular Weight:
633.74
Purity:
0.98
SMILES:
CS(O)(=O)=O.CC(=N)N1CCC(CC1)Oc1ccc(cc1)N(Cc1ccc2ccc(cc2c1)C(N)=N)S(=O)(=O)CC(O)=O

References

1. Sato K, Kaku S, Hirayama F, Koshio H, Matsumoto Y, Kawasaki T, Iizumi Y. Antithrombotic effect of YM-75466 is separated from its effect on bleeding time and coagulation time. Eur J Pharmacol. 1998 Jul 3;352(1):59-63. PubMed PMID: 9718268. 2. Sato K, Taniuchi Y, Kawasaki T, Hirayama F, Koshio H, Matsumoto Y, Iizumi Y. Comparison of the anticoagulant and antithrombotic effects of YM-75466, a novel orally-active factor Xa inhibitor, and warfarin in mice. Jpn J Pharmacol. 1998 Oct;78(2):191-7. PubMed PMID: 9829622. 3. Sato K, Taniuchi Y, Kawasaki T, Hirayama F, Koshio H, Matsumoto Y. Relationship between the antithrombotic effect of YM-75466, a novel factor Xa inhibitor, and coagulation parameters in rats. Eur J Pharmacol. 1998 Apr 24;347(2-3):231-6. PubMed PMID: 9653887.