TargetMol

ZD-8731 HCl

Product Code:
 
TAR-T29212
Product Group:
 
Inhibitors and Activators
Supplier:
 
TargetMol
Regulatory Status:
 
RUO
Shipping:
 
cool pack
Storage:
 
-20℃
1 / 1
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CodeSizePrice
TAR-T29212-5mg5mg£1,010.00
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TAR-T29212-50mg50mg£1,982.00
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Quantity:
TAR-T29212-100mg100mg£2,560.00
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This product comes from: United States.
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Further Information

Bioactivity:
ZD-8731, an angiotensin type 1 receptor antagonist, is used potentially for the treatment of hypertension and heart failure.
CAS:
135015-84-8
Formula:
C25H22ClN5O
Molecular Weight:
443.94
Purity:
0.98
SMILES:
Cl.CCc1cc(OCc2ccc(cc2)-c2ccccc2-c2nnn[nH]2)c2ccccc2n1

References

1. Geiger H, Fierlbeck W, Mai M, Ruchti H, Sch?nfeld V, D?mmrich J, Hugo C, Neumayer HH. Effects of early and late antihypertensive treatment on extracellular matrix proteins and mononuclear cells in uninephrectomized SHR. Kidney Int. 1997 Mar;51(3):750-61. PubMed PMID: 9067907. 2. Hoenack C, Roesen P. Inhibition of angiotensin type 1 receptor prevents decline of glucose transporter (GLUT4) in diabetic rat heart. Diabetes. 1996 Jan;45 Suppl 1:S82-7. PubMed PMID: 8529806. 3. Brilla CG, Zhou G, Rupp H, Maisch B, Weber KT. Role of angiotensin II and prostaglandin E2 in regulating cardiac fibroblast collagen turnover. Am J Cardiol. 1995 Nov 2;76(13):8D-13D. Review. PubMed PMID: 7495221. 4. Shaw LM, George PR, Oldham AA, Heagerty AM. A comparison of the effect of angiotensin converting enzyme inhibition and angiotensin II receptor antagonism on the structural changes associated with hypertension in rat small arteries. J Hypertens. 1995 Oct;13(10):1135-43. PubMed PMID: 8586805.