TargetMol

5-Hydroxydecanoate sodium

Product Code:
 
TAR-T29457L
Product Group:
 
Inhibitors and Activators
Supplier:
 
TargetMol
Regulatory Status:
 
RUO
Shipping:
 
cool pack
Storage:
 
-20℃
 

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CodeSizePrice
TAR-T29457L-10mg10mg£97.00
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TAR-T29457L-25mg25mg£117.00
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TAR-T29457L-1mL1 mL * 10 mM (in DMSO)£122.00
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TAR-T29457L-50mg50mg£148.00
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TAR-T29457L-100mg100mg£184.00
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TAR-T29457L-200mg200mg£242.00
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TAR-T29457L-500mg500mg£369.00
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This product comes from: United States.
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Further Information

Bioactivity:
5-Hydroxydecanoate sodium is a selective ATP-sensitive K+ (KATP) channel blocker with IC50 of about 30 μM. 5-Hydroxydecanoate sodium is a substrate for mitochondrial outer membrane acyl-CoA synthetase with antioxidant property.
CAS:
0
Formula:
C10H19NaO3
Molecular Weight:
210.25
Pathway:
Membrane transporter/Ion channel
Purity:
0.98
SMILES:
[Na+].CCCCCC(O)CCCC([O-])=O
Target:
Potassium Channel

References

1. Xiantao Li, et al. 5-Hydroxydecanoate and coenzyme A are inhibitors of native sarcolemmal KATP channels in inside-out patches. Biochim Biophys Acta. 2010 Mar;1800(3):385-91. 2. M G Marina Prendes, et al. Effects of 5-hydroxydecanoate and ischemic preconditioning on the ischemic-reperfused heart of fed and fasted rats. J Physiol Biochem. 2005 Sep;61(3):447-56. 3. Congna Zi, et al. Penehyclidine hydrochloride protects against anoxia/reoxygenation injury in cardiomyocytes through ATP-sensitive potassium channels, and the Akt/GSK-3? and Akt/mTOR signaling pathways. Cell Biol Int. 2020 Jun;44(6):1353-1362.