TargetMol

5-OH-HxMF

Product Code:
 
TAR-T29462
Supplier:
 
TargetMol
Regulatory Status:
 
RUO
Shipping:
 
cool pack
Storage:
 
-20℃
1 / 1
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CodeSizePrice
TAR-T29462-5mg5mg£850.00
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TAR-T29462-50mg50mg£1,661.00
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Quantity:
TAR-T29462-100mg100mg£2,079.00
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Further Information

Bioactivity:
5-OH-HxMF is an inducer of neurite growth in PC12 cells through the camp / PKA / CREB pathway.
CAS:
1176-88-1
Formula:
C21H22O9
Molecular Weight:
418.398
Purity:
0.98
SMILES:
COc1ccc(cc1OC)-c1oc2c(OC)c(OC)c(OC)c(O)c2c(=O)c1OC

References

1. Wang Y, Lee PS, Chen YF, Ho CT, Pan MH. Suppression of Adipogenesis by 5-Hydroxy-3,6,7,8,3',4'-Hexamethoxyflavone from Orange Peel in 3T3-L1 Cells. J Med Food. 2016 Sep;19(9):830-5. doi: 10.1089/jmf.2016.0060. Epub 2016 Aug 19. PubMed PMID: 27542074. 2. Wang X, Xia M. 5-Hydroxy-3,6,7,8,3',4'-hexamethoxyflavone, a polymethoxyflavone, exerts antitumor effect on PI3K/Akt signaling pathway in human gastric cancer cell BGC-7901. J Recept Signal Transduct Res. 2016 Oct;36(5):471-7. doi: 10.3109/10799893.2015.1122046. Epub 2015 Dec 16. PubMed PMID: 26671739. 3. Wu CH, Hong BH, Ho CT, Yen GC. Targeting cancer stem cells in breast cancer: potential anticancer properties of 6-shogaol and pterostilbene. J Agric Food Chem. 2015 Mar 11;63(9):2432-41. doi: 10.1021/acs.jafc.5b00002. Epub 2015 Feb 25. PubMed PMID: 25686711. 4. Kim MJ, Lee HH, Jeong JW, Seo MJ, Kang BW, Park JU, Kim KS, Cho YS, Seo KI, Kim GY, Kim JI, Choi YH, Jeong YK. Anti-inflammatory effects of 5-hydroxy-3,6,7,8,3',4'-hexamethoxyflavone via NF-?B inactivation in lipopolysaccharide-stimulated RAW 264.7 macrophage. Mol Med Rep. 2014 Apr;9(4):1197-203. doi: 10.3892/mmr.2014.1922. Epub 2014 Jan 28. PubMed PMID: 24481726.