TargetMol

ADR-925

Product Code:
 
TAR-T29670
Product Group:
 
Inhibitors and Activators
Supplier:
 
TargetMol
Regulatory Status:
 
RUO
Shipping:
 
cool pack
Storage:
 
-20℃
1 / 1
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CodeSizePrice
TAR-T29670-1mg1mg£970.00
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TAR-T29670-5mg5mg£1,878.00
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TAR-T29670-10mg10mg£2,456.00
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TAR-T29670-25mg25mg£3,677.00
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TAR-T29670-50mg50mg£4,866.00
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This product comes from: United States.
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Further Information

Bioactivity:
ADR-925 is an active iron-chelating metabolite of dexrazoxane.
CAS:
75459-34-6
Formula:
C11H20N4O6
Molecular Weight:
304.303
Pathway:
Metabolism
Purity:
0.98
SMILES:
C[C@@H](CN(CC(N)=O)CC(O)=O)N(CC(N)=O)CC(O)=O
Target:
Endogenous Metabolite

References

1. St?rba M, Popelov? O, V?vrov? A, Jirkovsk? E, Kova??kov? P, Ger?l V, Sim?nek T. Oxidative stress, redox signaling, and metal chelation in anthracycline cardiotoxicity and pharmacological cardioprotection. Antioxid Redox Signal. 2013 Mar 10;18(8):899-929. doi: 10.1089/ars.2012.4795. Epub 2012 Oct 12. Review. PubMed PMID: 22794198; PubMed Central PMCID: PMC3557437. 2. Sim?nek T, St?rba M, Popelov? O, Adamcov? M, Hrdina R, Gersl V. Anthracycline-induced cardiotoxicity: overview of studies examining the roles of oxidative stress and free cellular iron. Pharmacol Rep. 2009 Jan-Feb;61(1):154-71. Review. PubMed PMID: 19307704. 3. Lopez M. [Development of cancer chemotherapy. Cytoprotective agents]. Clin Ter. 2001 Mar-Apr;152(2):135-43. Review. Italian. PubMed PMID: 11441524. 4. Hochster HS. Clinical pharmacology of dexrazoxane. Semin Oncol. 1998 Aug;25(4 Suppl 10):37-42. Review. PubMed PMID: 9768822.