TargetMol

AG 127

Product Code:
 
TAR-T29696
Product Group:
 
Inhibitors and Activators
Supplier:
 
TargetMol
Regulatory Status:
 
RUO
Shipping:
 
cool pack
Storage:
 
-20℃
1 / 1

No additional charges, what you see is what you pay! *

CodeSizePrice
TAR-T29696-5mg5mg£850.00
Special offer! Add £1 to your order to get a TargetMol CCK-8 Kit. Read more here.
Quantity:
Prices exclude any Taxes / VAT
Stay in control of your spending. These prices have no additional charges, not even shipping!
* Rare exceptions are clearly labelled (only 0.14% of items!).
Multibuy discounts available! Contact us to find what you can save.
This product comes from: United States.
Typical lead time: 10-14 working days.
Contact us for more accurate information.
  • Further Information
  • Documents
  • References
  • Show All

Further Information

Bioactivity:
AG 127 is a biochemical.
CAS:
90947-89-0
Formula:
C10H5N3O3
Molecular Weight:
215.168
Purity:
0.98
SMILES:
Oc1ccc(C=C(C#N)C#N)cc1[N+]([O-])=O

References

1. Menzfeld C, John M, van Rossum D, Regen T, Scheffel J, Janova H, G?tz A, Ribes S, Nau R, Borisch A, Boutin P, Neumann K, Bremes V, Wienands J, Reichardt HM, L?hder F, Tischner D, Waetzig V, Herdegen T, Teismann P, Greig I, M?ller M, Pukrop T, Mildner A, Kettenmann H, Br?ck W, Prinz M, Rotshenker S, Weber MS, Hanisch UK. Tyrphostin AG126 exerts neuroprotection in CNS inflammation by a dual mechanism. Glia. 2015 Jun;63(6):1083-99. doi: 10.1002/glia.22803. Epub 2015 Mar 2. PubMed PMID: 25731696. 2. Voss K, Amaya M, Mueller C, Roberts B, Kehn-Hall K, Bailey C, Petricoin E 3rd, Narayanan A. Inhibition of host extracellular signal-regulated kinase (ERK) activation decreases new world alphavirus multiplication in infected cells. Virology. 2014 Nov;468-470:490-503. doi: 10.1016/j.virol.2014.09.005. Epub 2014 Sep 27. PubMed PMID: 25261871. 3. Koss DJ, Riedel G, Bence K, Platt B. Store-operated Ca2+ entry in hippocampal neurons: Regulation by protein tyrosine phosphatase PTP1B. Cell Calcium. 2013 Feb;53(2):125-38. doi: 10.1016/j.ceca.2012.11.004. Epub 2012 Dec 4. PubMed PMID: 23218930. 4. Turpaev K, Ermolenko M, Cresteil T, Drapier JC. Benzylidenemalononitrile compounds as activators of cell resistance to oxidative stress and modulators of multiple signaling pathways. A structure-activity relationship study. Biochem Pharmacol. 2011 Sep 1;82(5):535-47. doi: 10.1016/j.bcp.2011.05.028. Epub 2011 Jun 2. PubMed PMID: 21669191.