TargetMol

Alilusem

Product Code:
 
TAR-T29864
Product Group:
 
Inhibitors and Activators
Supplier:
 
TargetMol
Regulatory Status:
 
RUO
Shipping:
 
cool pack
Storage:
 
-20℃
1 / 1
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CodeSizePrice
TAR-T29864-5mg5mg£850.00
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Quantity:
TAR-T29864-50mg50mg£1,661.00
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Quantity:
TAR-T29864-100mg100mg£2,079.00
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This product comes from: United States.
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Further Information

Bioactivity:
Alilusem is a new diuretic that is beneficial to the clinical treatment of hypertension.
CAS:
114417-20-8
Formula:
C17H15ClN2O5S
Molecular Weight:
394.83
Purity:
0.98
SMILES:
Cc1ccccc1C(=O)N1CCC(=N/OS(O)(=O)=O)c2ccc(Cl)cc12

References

1. Nishimura T, Kubo Y, Kato Y, Sai Y, Ogihara T, Tsuji A. Characterization of the uptake mechanism for a novel loop diuretic, M17055, in Caco-2 cells: involvement of organic anion transporting polypeptide (OATP)-B. Pharm Res. 2007 Jan;24(1):90-8. Epub 2006 Nov 14. PubMed PMID: 17103337. 2. Nishimura T, Kato Y, Sai Y, Ogihara T, Tsuji A. Characterization of renal excretion mechanism for a novel diuretic, M17055, in rats. J Pharm Sci. 2004 Oct;93(10):2558-66. PubMed PMID: 15349965. 3. Nakajima H, Nakanishi T, Naba H, Nakai K, Matsumoto S, Nagasawa K, Ida K, Ogihara T, Ohzawa N. Studies on the metabolic fate of M17055, a novel diuretic (6). Assessment for drug-drug interactions of M17055 in metabolism, distribution and excretion. Xenobiotica. 2002 Dec;32(12):1161-72. PubMed PMID: 12593763. 4. Kim S, Hamaguchi A, Shinkawa T, Kato Y, Tsuchiya N, Miura K, Ohta K, Iwao H. Molecular effects of M17055, furosemide and thiazide on cardiac hypertrophy of spontaneously hypertensive rats. J Pharmacol Exp Ther. 1996 Nov;279(2):983-90. PubMed PMID: 8930208.