TargetMol

ALK-001

Product Code:
 
TAR-T29867
Product Group:
 
Inhibitors and Activators
Supplier:
 
TargetMol
Regulatory Status:
 
RUO
Shipping:
 
cool pack
Storage:
 
-20℃
1 / 1
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CodeSizePrice
TAR-T29867-5mg5mg£850.00
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Further Information

Bioactivity:
ALK-001 is a vitamin A analog, which may be used to treat Stargardt disease.
CAS:
118139-36-9
Formula:
C22H32O2
Molecular Weight:
331.514
Purity:
0.98
SMILES:
[2H]C([2H])([2H])C(=C/COC(C)=O)C=CC=C(/C)C=CC1=C(C)CCCC1(C)C

References

1. Saad L, Washington I. Can Vitamin A be Improved to Prevent Blindness due to Age-Related Macular Degeneration, Stargardt Disease and Other Retinal Dystrophies? Adv Exp Med Biol. 2016;854:355-61. doi: 10.1007/978-3-319-17121-0_47. PubMed PMID: 26427432. 2. Charbel Issa P, Barnard AR, Herrmann P, Washington I, MacLaren RE. Rescue of the Stargardt phenotype in Abca4 knockout mice through inhibition of vitamin A dimerization. Proc Natl Acad Sci U S A. 2015 Jul 7;112(27):8415-20. doi: 10.1073/pnas.1506960112. PubMed PMID: 26106163; PubMed Central PMCID: PMC4500285.