TargetMol

AMG-126737

Product Code:
 
TAR-T29969
Product Group:
 
Inhibitors and Activators
Supplier:
 
TargetMol
Regulatory Status:
 
RUO
Shipping:
 
cool pack
Storage:
 
-20℃
1 / 1
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CodeSizePrice
TAR-T29969-5mg5mg£850.00
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Further Information

Bioactivity:
AMG-126737 is an effective human lung mast cell trypsin inhibitor with potential therapeutic effect in lung diseases.
CAS:
224054-76-6
Formula:
C33H38N6O6S2
Molecular Weight:
678.82
Purity:
0.98
SMILES:
NC(=N)c1cccc(c1)S(=O)(=O)NCc1ccc(OCCCCCOc2ccc(CNS(=O)(=O)c3cccc(c3)C(N)=N)cc2)cc1

References

1. Wright CD, Havill AM, Middleton SC, Kashem MA, Dripps DJ, Abraham WM, Thomson DS, Burgess LE. Inhibition of allergen-induced pulmonary responses by the selective tryptase inhibitor 1,5-bis-[4-[(3-carbamimidoyl-benzenesulfonylamino)-methyl]-phenoxy]-pen tane (AMG-126737). Biochem Pharmacol. 1999 Dec 15;58(12):1989-96. PubMed PMID: 10591155.