TargetMol

AP-22161

Product Code:
 
TAR-T30089
Product Group:
 
Inhibitors and Activators
Supplier:
 
TargetMol
Regulatory Status:
 
RUO
Shipping:
 
cool pack
Storage:
 
-20℃
1 / 1
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CodeSizePrice
TAR-T30089-5mg5mg£1,653.00
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TAR-T30089-50mg50mg£3,267.00
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Quantity:
TAR-T30089-100mg100mg£4,488.00
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This product comes from: United States.
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Further Information

Bioactivity:
AP-22161 selectively binds the Src SH2 domain by targeting highly conserved phosphotyrosine binding to cysteine residues in the pocket. AP-22161 selectively inhibits Src SH2 binding and can be used to inhibit osteoclast absorption.
CAS:
268741-42-0
Formula:
C32H39N3O7
Molecular Weight:
577.678
Purity:
0.98
SMILES:
CC(=O)NC(Cc1ccc(C(O)=O)c(C=O)c1)C(=O)NC1CCCCc2cc(OCC3CCCCC3)c(cc12)C(N)=O

References

1. Violette SM, Shakespeare WC, Bartlett C, Guan W, Smith JA, Rickles RJ, Bohacek RS, Holt DA, Baron R, Sawyer TK. A Src SH2 selective binding compound inhibits osteoclast-mediated resorption. Chem Biol. 2000 Mar;7(3):225-35. PubMed PMID: 10712930.