TargetMol

AT 61

Product Code:
 
TAR-T30185
Product Group:
 
Inhibitors and Activators
Supplier:
 
TargetMol
Regulatory Status:
 
RUO
Shipping:
 
cool pack
Storage:
 
-20℃
1 / 1
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CodeSizePrice
TAR-T30185-5mg5mg£850.00
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Quantity:
TAR-T30185-50mg50mg£1,661.00
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Quantity:
TAR-T30185-100mg100mg£2,079.00
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This product comes from: United States.
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Further Information

Bioactivity:
AT-61 is a nonnucleoside analogue inhibitor of hepatitis B virus (HBV) replication.
CAS:
300669-68-5
Formula:
C21H21ClN2O2
Molecular Weight:
368.86
Purity:
0.98
SMILES:
ClC(=C(NC(=O)c1ccccc1)C(=O)N1CCCCC1)c1ccccc1

References

1. Delaney WE 4th, Edwards R, Colledge D, Shaw T, Furman P, Painter G, Locarnini S. Phenylpropenamide derivatives AT-61 and AT-130 inhibit replication of wild-type and lamivudine-resistant strains of hepatitis B virus in vitro. Antimicrob Agents Chemother. 2002 Sep;46(9):3057-60. PubMed PMID: 12183271; PubMed Central PMCID: PMC127422. 2. King RW, Ladner SK, Miller TJ, Zaifert K, Perni RB, Conway SC, Otto MJ. Inhibition of human hepatitis B virus replication by AT-61, a phenylpropenamide derivative, alone and in combination with (-)beta-L-2',3'-dideoxy-3'-thiacytidine. Antimicrob Agents Chemother. 1998 Dec;42(12):3179-86. Erratum in: Antimicrob Agents Chemother 1999 Mar;43(3):726. PubMed PMID: 9835512; PubMed Central PMCID: PMC106020.