TargetMol

BMS-561392

Product Code:
 
TAR-T30531
Product Group:
 
Inhibitors and Activators
Supplier:
 
TargetMol
Regulatory Status:
 
RUO
Shipping:
 
cool pack
Storage:
 
-20℃
1 / 1
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CodeSizePrice
TAR-T30531-1mg1mg£227.00
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TAR-T30531-5mg5mg£430.00
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TAR-T30531-1mL1 mL * 10 mM (in DMSO)£495.00
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TAR-T30531-10mg10mg£613.00
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TAR-T30531-25mg25mg£997.00
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Further Information

Bioactivity:
BMS-561392 is a tumor necrosis factor- α ( TNF α) Invertase inhibitor.
CAS:
611227-74-8
Formula:
C15H16FNO5
Molecular Weight:
309.29
Pathway:
Apoptosis
Purity:
0.98
SMILES:
CC1=NC2=CC=CC=C2C(=C1)COC3=CC=C(C=C3)[C@@]4(CCN(C4=O)[C@H](CC(C)C)C(=O)NO)N
Target:
TNF

References

Sharma M, et al. Blockade of tumor necrosis factor-? converting enzyme (TACE) enhances IL-1? and IFN-? via caspase-1 activation: a probable cause for loss of efficacy of TACE inhibitors in humans? Eur J Pharmacol. 2013 Feb 15;701(1-3):106-13. Sharma M, et al. Selective inhibition of tumor necrosis factor-? converting enzyme attenuates liver toxicity in a murine model of concanavalin A induced auto-immune hepatitis. Int Immunopharmacol. 2013 Oct;17(2):229-36. Vidal PM, et al. ADAM17 is a survival factor for microglial cells in vitro and in vivo after spinal cord injury in mice. Cell Death Dis. 2013 Dec 12;4:e954. Fong KP, et al. Deciphering the human platelet sheddome. Blood. 2011 Jan 6;117(1):e15-26.