TargetMol

Bufuralol

Product Code:
 
TAR-T30611
Product Group:
 
Inhibitors and Activators
Supplier:
 
TargetMol
Regulatory Status:
 
RUO
Shipping:
 
cool pack
Storage:
 
-20℃
1 / 1
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CodeSizePrice
TAR-T30611-5mg5mg£357.00
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TAR-T30611-50mg50mg£1,669.00
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Quantity:
TAR-T30611-100mg100mg£2,633.00
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This product comes from: United States.
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Further Information

Bioactivity:
Bufuralol is a Adrenergic Agent.
CAS:
54340-62-4
Formula:
C16H23NO2
Molecular Weight:
261.365
Purity:
0.98
SMILES:
CCc1cccc2cc(oc12)C(O)CNC(C)(C)C

References

1. Uehara S, Uno Y, Hagihira Y, Murayama N, Shimizu M, Inoue T, Sasaki E, Yamazaki H. Marmoset cytochrome P450 2D8 in livers and small intestines metabolizes typical human P450 2D6 substrates, metoprolol, bufuralol and dextromethorphan. Xenobiotica. 2015;45(9):766-72. doi: 10.3109/00498254.2015.1019595. Epub 2015 Jul 27. PubMed PMID: 25801057. 2. Cai J, Dai DP, Geng PW, Wang SH, Wang H, Zhan YY, Huang XX, Hu GX, Cai JP. Effects of 22 Novel CYP2D6 Variants Found in the Chinese Population on the Bufuralol and Dextromethorphan Metabolisms In Vitro. Basic Clin Pharmacol Toxicol. 2016 Mar;118(3):190-9. doi: 10.1111/bcpt.12478. Epub 2015 Sep 26. PubMed PMID: 26310775. 3. Pringle TH, Francis RJ, East PB, Shanks RG. Pharmacodynamic and pharmacokinetic studies on bufuralol in man. Br J Clin Pharmacol. 1986 Nov;22(5):527-34. PubMed PMID: 2878678; PubMed Central PMCID: PMC1401192. 4. Johnston GD, Finch MB, Shanks RG. Peripheral vascular effects of bufuralol in hypertensive and normal subjects: a comparison with propranolol and pindolol. Eur J Clin Pharmacol. 1986;30(6):649-52. PubMed PMID: 3533562.