TargetMol

C012 Dihydrochloride

Product Code:
 
TAR-T30676
Product Group:
 
Inhibitors and Activators
Supplier:
 
TargetMol
Regulatory Status:
 
RUO
Shipping:
 
cool pack
Storage:
 
-20℃
1 / 1
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CodeSizePrice
TAR-T30676-5mg5mg£850.00
Special offer! Add £1 to your order to get a TargetMol CCK-8 Kit. Read more here.
Quantity:
TAR-T30676-50mg50mg£1,661.00
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Quantity:
TAR-T30676-100mg100mg£2,079.00
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Quantity:
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This product comes from: United States.
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Further Information

Bioactivity:
C012 Dihydrochloride is a novel small molecule compound that sensitized BRAF wild-type melanoma cells to verofenib. It can significantly reduce the activity of melanoma cells and has limited toxicity to normal human fibroblasts.
CAS:
1219163-50-4
Formula:
C23H30Cl2N4O
Molecular Weight:
449.42
Purity:
0.98
SMILES:
Cl.Cl.CCOc1ccc(cc1)-c1cn2c(n1)n(CCN(CC)CC)c1ccccc21

References

1. Sutton SK, Carter DR, Kim P, et al. A novel compound which sensitizes BRAF wild-type melanoma cells to vemurafenib in a TRIM16-dependent manner. Oncotarget. 2016;7(32):52166-52178. doi:10.18632/oncotarget.10700.