TargetMol

Carboetomidate

Product Code:
 
TAR-T30741
Product Group:
 
Inhibitors and Activators
Supplier:
 
TargetMol
Regulatory Status:
 
RUO
Shipping:
 
cool pack
Storage:
 
-20℃
1 / 1
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CodeSizePrice
TAR-T30741-5mg5mg£850.00
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TAR-T30741-50mg50mg£1,661.00
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Quantity:
TAR-T30741-100mg100mg£2,079.00
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This product comes from: United States.
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Further Information

Bioactivity:
Carboetomidate is an analog of etomidate and does not bind to 11β -hydroxylase with high affinity.
CAS:
1257067-10-9
Formula:
C15H17NO2
Molecular Weight:
243.306
Purity:
0.98
SMILES:
CCOC(=O)c1cccn1[C@H](C)c1ccccc1

References

1. Khurmi N, Patel P, Kraus M, Trentman T. Pharmacologic Considerations for Pediatric Sedation and Anesthesia Outside the Operating Room: A Review for Anesthesia and Non-Anesthesia Providers. Paediatr Drugs. 2017 Oct;19(5):435-446. doi: 10.1007/s40272-017-0241-5. Review. PubMed PMID: 28597354. 2. Pejo E, Zhou X, Husain SS, Raines DE. Sedative-hypnotic Binding to 11?-hydroxylase. Anesthesiology. 2016 Nov;125(5):943-951. PubMed PMID: 27541316; PubMed Central PMCID: PMC5069162. 3. Shanmugasundararaj S, Zhou X, Neunzig J, Bernhardt R, Cotten JF, Ge R, Miller KW, Raines DE. Carboetomidate: an analog of etomidate that interacts weakly with 11?-hydroxylase. Anesth Analg. 2013 Jun;116(6):1249-56. doi: 10.1213/ANE.0b013e31828b3637. Epub 2013 Mar 14. PubMed PMID: 23492967; PubMed Central PMCID: PMC3836822. 4. Desai R, Miller KW, Raines DE. The pyrrole etomidate analog carboetomidate potently inhibits human 5-HT3A receptor function: comparisons with etomidate and potential implications for emetogenesis. Anesth Analg. 2013 Mar;116(3):573-9. doi: 10.1213/ANE.0b013e31827d204d. Epub 2013 Feb 11. PubMed PMID: 23400978; PubMed Central PMCID: PMC3582768.