TargetMol

CB 30900

Product Code:
 
TAR-T30760
Product Group:
 
Inhibitors and Activators
Supplier:
 
TargetMol
Regulatory Status:
 
RUO
Shipping:
 
cool pack
Storage:
 
-20℃
1 / 1
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CodeSizePrice
TAR-T30760-5mg5mg£1,412.00
Special offer! Add £1 to your order to get a TargetMol CCK-8 Kit. Read more here.
Quantity:
TAR-T30760-50mg50mg£2,785.00
Special offer! Add £1 to your order to get a TargetMol CCK-8 Kit. Read more here.
Quantity:
TAR-T30760-100mg100mg£3,765.00
Special offer! Add £1 to your order to get a TargetMol CCK-8 Kit. Read more here.
Quantity:
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This product comes from: United States.
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  • Further Information
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Further Information

Bioactivity:
CB30900 is a novel and effective thymidylate synthase inhibitor.
CAS:
145788-82-5
Formula:
C31H32FN5O9
Molecular Weight:
637.621
Purity:
0.98
SMILES:
Cc1nc(=O)c2cc(CN(CC#C)c3ccc(C(=O)N[C@@H](CCC(=O)N[C@H](CCC(O)=O)C(O)=O)C(O)=O)c(F)c3)c(C)cc2[nH]1

References

1. Aherne GW, Hardcastle A, Raynaud F, Jackman AL. Immunoreactive dUMP and TTP pools as an index of thymidylate synthase inhibition; effect of tomudex (ZD1694) and a nonpolyglutamated quinazoline antifolate (CB30900) in L1210 mouse leukaemia cells. Biochem Pharmacol. 1996 May 17;51(10):1293-301. PubMed PMID: 8787544. 2. Walton MI, Gibson W, Aherne GW, Lawrence N, Stephens TC, Smith MN, Jackman AL. Preclinical pharmacology of CB30900, a novel dipeptide inhibitor of thymidylate synthase, in mice. J Pharmacol Exp Ther. 1996 May;277(2):909-16. PubMed PMID: 8627573.