TargetMol

CI-925

Product Code:
 
TAR-T30926
Product Group:
 
Inhibitors and Activators
Supplier:
 
TargetMol
Regulatory Status:
 
RUO
Shipping:
 
cool pack
Storage:
 
-20℃
1 / 1
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CodeSizePrice
TAR-T30926-5mg5mg£850.00
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This product comes from: United States.
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Further Information

Bioactivity:
CI-925 is an angiotensin converting enzyme inhibitor with antihypertensive activity. It also prevents the release of aldosterone by the adrenal cortex induced by angiotensin II.
CAS:
109715-88-0
Formula:
C27H34N2O7
Molecular Weight:
498.576
Purity:
0.98
SMILES:
CCOC(=O)[C@H](CCc1ccccc1)N[C@@H](C)C(=O)N1Cc2cc(OC)c(OC)cc2C[C@H]1C(O)=O

References

1. Cameron RT, Coleman RG, Day JP, Yalla KC, Houslay MD, Adams DR, Shoichet BK, Baillie GS. Chemical informatics uncovers a new role for moexipril as a novel inhibitor of cAMP phosphodiesterase-4 (PDE4). Biochem Pharmacol. 2013 May 1;85(9):1297-305. doi: 10.1016/j.bcp.2013.02.026. Epub 2013 Mar 5. PubMed PMID: 23473803; PubMed Central PMCID: PMC3625111. 2. Karra VK, Mullangi R, Pilli NR, Inamadugu JK, Ravi VB, Seshagiri Rao JV. A rapid and sensitive liquid chromatography-tandem mass spectrometric assay for moexipril, an angiotensin-converting enzyme inhibitor in human plasma. Biomed Chromatogr. 2012 Dec;26(12):1552-8. doi: 10.1002/bmc.2731. Epub 2012 Mar 14. PubMed PMID: 22419504.